The generalized Shwartzman phenomenon in rats.
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چکیده
منابع مشابه
Platelets and the Shwartzman Phenomenon
Studies are reported on the effect of immunologically induced thrombocytopenia upon the local and generalized Shwartzman phenomena. Intravenous injection of antiplatelet serum to rabbits produced profound but transient thrombocytopenia unaccompanied by significant changes in circulating leucocytes. Platelet antiserum alone given to rabbits prepared with thorotrast produced renal lesions charact...
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Endotoxin-neutralizing activity may be an important property for antibiotics to be used in severe sepsis. Several antibiotics, belonging to different classes, were evaluated as to their endotoxin-neutralizing ability, using the inhibition of an in vitro metachromatic assay for lipopolysaccharides and a murine generalized Shwartzman reaction model. Gentamicin, amikacin, and sisomicin have been f...
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By F. RODRIGUEZ-ERDMANN T HE SANARELLI-SHWARTZMAN phenomenon-generalized Shwartzman reaction (GSR )-is observed in rabbits after two properly spaced intravenous injections of endotoxin derived from gram-negative bacteria and is characterized by profound collapse and hemorrhagic diathesis. Marked changes in the blood clotting mechanism in animals undergoing GSR have been described’6’30’35 and re...
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By F. RODRIGUEZ-ERDMANN T HE SANARELLI-SHWARTZMAN phenomenon-generalized Shwartzman reaction (GSR )-is observed in rabbits after two properly spaced intravenous injections of endotoxin derived from gram-negative bacteria and is characterized by profound collapse and hemorrhagic diathesis. Marked changes in the blood clotting mechanism in animals undergoing GSR have been described’6’30’35 and re...
متن کاملStudies of the Generalized Shwartzman Reaction Produced by Diet
By molecular distillation of oxidized cod liver oil a partial isolation of the lipid species responsible for the diet-induced generalized Shwartzman reaction in pregnant rats has been achieved. Molecular distillation produced three fractions and a residue. Qualitative and quantitative differences in each fraction were shown by determining iodine and saponification numbers and by thin layer chro...
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عنوان ژورنال:
- A.M.A. archives of pathology
دوره 62 4 شماره
صفحات -
تاریخ انتشار 1956